EVERYTHING ABOUT CEESDEKKER

Everything about ceesdekker

Everything about ceesdekker

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Nanotechnology presents An array of alternatives to add to biology. Here I will present examples in which nanofabrication – the chance to make confined buildings with Proportions at will – is made use of to look at the biophysics of one molecules and cells. I'll current some illustrations from our lab:

1996, 1st mesoscopic demand density waves gadgets; and 1st electrical measurements on only one steel nanocluster involving nanoelectrodes

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Non-equilibrium folding of person DNA molecules recaptured around 1000 occasions inside a strong state nanopore

This yielded a breakthrough. Within just only a few months, we ended up capable of evaluate transport as a result of a person one-walled carbon nanotube. Depending on low-temperature experiments by an excellent PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Engineering having an active exploration lab at AMOLF in Amsterdam), we showed that carbon nanotubes have been genuine quantum wires with quite lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.

The coiled-coil of the human Rad50 DNA repair service protein is made up of specific segments of greater versatility

We use nanofabricated microfluidic buildings to sample spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks which assess the basic job of spatial confinement in the molecular and mobile level. Our projects consist of the subsequent:

Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation

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Really neat, but that wasn’t truly the place my desire lay. I desired to pioneer and I experienced the sensation which was no longer achievable, since the most interesting fundamental insights had previously been uncovered. But my industry experienced created a lot of enjoyable new tools to measure personal molecules. I decided which i desired to utilize this to biology, to have a look at it from the physical point of view.’

[fourteen] In 2005 Dekker turned associated with Netherlands-large discussions about Smart Design, a movement that he has due to the fact clearly distanced himself from. Dekker advocates that science and religion are usually not in opposition but could be harmonized.

Nanoscientist Cees Dekker is surely an amiable and flamboyant guy who seems Substantially youthful compared to 62 decades he essentially is – stylish glasses, psychedelic shirt, partaking smile – but not one to squander time. He normally takes his time, but no more than vital.

2008, initial observation of protein-coated DNA translocation via nanopores; ceesdekker resolved the origin of the electrophoretic drive on DNA in nanopores; found out a big velocity raise of microtubules in electrical fields; identified an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid

2004, discovery of new physics in translocation of DNA by way of nanopores; first experimental review of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; very first biophysics characterization of your mechanical Homes of double-stranded RNA; and to start with single-molecule review of DNA translocation by a restriction-modification enzyme.

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